Prospective BrM tissue
Identify newly resected brain metastases and bank fresh, frozen, or FFPE material when consent and institutional pathways allow.
TRACE: Contribute Samples and Data
TRACE — Tissue Retrieval and Analysis for Cancer Evolution — coordinates eligible brain metastasis tissue retrieval, matched archival primary tumor tissue/data, recurrent disease tracking, and linked clinical, imaging, pathology, and molecular data.
Longitudinal matching
Retrieve matched archival primary tumors, recurrent intracranial disease, extracranial metastases, normal samples, and treatment timelines.
Data readiness
Link clinical annotation, imaging, pathology, sequencing, and molecular pathology data for BRIDGE/TRACE registration and governance review.
What TRACE seeks
Newly resected brain metastases
Matched archival primary tumors
Recurrent brain metastases after surgery/SRS/systemic therapy
Extracranial metastases
Blood/saliva normal samples
Imaging
Clinical annotation and treatment timelines
Existing sequencing or molecular pathology data
TRACE operational workflow
- Identify eligible BrM case.
- Confirm consent/IRB pathway.
- Bank fresh/frozen/FFPE BrM tissue when available.
- Retrieve matched archival primary tumor tissue/data.
- Link clinical, imaging, pathology, and molecular data.
- Register dataset in BRIDGE/TRACE tracking system.
- Deposit appropriate data into public or controlled repositories.
Contact BRIDGE coordination team
Please contact the coordination team before shipping samples, transferring data, or initiating repository submission so that consent, IRB, data-use, and contributor-protection requirements can be aligned early.
- Lin coordination contact
- Institute of Systems Medicine / PUMC
BRIDGE@ism.pumc.edu.cn - Aaron coordination contact
- University of California, San Francisco
BRIDGE@ucsf.edu